While noninvasive prenatal testing (NIPT) has revolutionized prenatal diagnostics by allowing the detection of a number of genetic problems in a fetus, it is currently limited and thus misses many genetic causes of abnormalities. But a new technique, to be presented at the annual conference of the European Society of Human Genetics, introduces a technology called noninvasive fetal sequencing (NIFS) that will simultaneously screen almost 23,000 genes, as well as all of the conditions currently captured by NIPT, in pregnancies both with and without a previously detected fetal anomaly.
Researchers at the Monell Chemical Senses Center have found that common dietary sugars fructose and glucose, despite having the same number of calories, communicate with the brain through different gut–brain pathways, a difference that may help shape our food and beverage preferences. In mice, the team identified a dedicated gut-brain signaling pathway through which fructose communicates with the brain and found that it is much less effective than glucose in turning down the activity of hunger-related neurons.
Depression is a serious mental health issue that can rob us of joy—and years of healthy living. While we know depressive symptoms can cut the remaining years of disability-free living (or "healthspan") in older adults, it was unclear exactly which symptoms could be the culprit.
Treatment of a serious mental illness that can lead to suicide, such as major depressive disorder, often centers on medication and talk therapy with little or no consideration of factors such as social isolation or financial duress. Now, there's a growing movement to address loneliness not just through personal choices but also through public policy.
The 2025 executive order dismantling U.S. Agency for International Development programs canceled 90% of the agency's contracts and grants, destabilizing health systems globally.
Some might joke about Tourette syndrome, but it's hellish for those who have the condition, a new report says. In all, 1 in 4 teens and adults with Tourette or other tic disorders have attempted suicide at some point in their lives, according to the Tourette Association of America's 2026 Impact Survey Report.
JMIR Publications today released an article on a brief, scalable intervention for post-traumatic stress disorder in its News and Perspectives section. Authored by JMIR correspondent Candice Marie Sage, Ph.D., "Written Exposure Therapy as Transformative, Scalable Care for Post-Traumatic Stress Disorder" reports how Written Exposure Therapy (WET) can bridge the gap in accessing effective PTSD treatment.
As more than 40% of American teenagers report persistent feelings of sadness or hopelessness, a leading child psychologist says that grandparents and extended family have a vital role to play.
A new test provides a much more complete picture of DNA than current standard diagnostics and leads to a diagnosis more often. The test can replace 15 other tests, making it faster and more efficient. Researchers from Radboud university medical center recommend in the New England Journal of Medicine that this test be adopted everywhere as the first choice for rare genetic disorders.
Women with HIV most often die from preventable, trauma-related conditions like substance use and mental illness—not the virus itself. Yet these leading causes are largely missing from official death records, according to new research by UC San Francisco.
Scientists at Florida International University may have found a way to make a powerful cancer treatment work even better. The treatment, called CAR-T therapy, uses a patient's own immune cells to fight cancer. Doctors remove special immune cells called T-cells from the body, genetically change them in a lab so they can recognize cancer, and then put them back into the patient to attack tumors. The therapy has already helped many people with serious blood cancers such as lymphoma and leukemia.
A research team at Lund University in Sweden has studied how patients with advanced cancer seek care during the final stages of their lives. By studying their care patterns, the research team has developed a measurement method that relates health care needs to the changing value of time for patients at the end of life. The less time they have left to live, the more precious time feels. The work is published in the journal Value in Health.
Some subgroups of children with precocious puberty—such as older girls with slowly progressing puberty—may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.
Always losing your way, even in places you've been visiting for years? You may have Developmental Topographical Disorientation (DTD). Psychologists from Leiden are investigating this relatively little-known condition at the Lowlands festival. "The ideal place to study getting lost."
Northwestern Medicine scientists have identified a safety concern associated with GLP-1 drugs. Using health record data, the research team tracked more than 42,000 adults already taking at least two types of blood pressure medications. After starting GLP-1s, these patients experienced higher rates of dizziness, fainting and other events related to low blood pressure, also known as hypotension.
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