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Genetic Engineering and Biology News Posts

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Data Integrity as the Foundation for AI

In this sponsored podcast, LabVantage’s Gary Stimson digs into what it takes to build a data foundation for trustworthy AI.

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Manus and UT Austin Advance Biomanufacturing Product Recovery Through BioMADE Program

A new study showed that a programmed lysis approach cut mechanical separation energy by over 50 percent at pilot scale, widening the range of bioalternatives that can compete pricewise.

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Chronic Interferon Exposure Linked to Immunosuppression in Cancer

A preclinical study uncovered a novel pathway that links chronic IFN-II exposure to mitochondrial dysfunction and ultimately immunosuppression in cancer, creating foundational insights that may point to future therapies that combat immunotherapy resistance.

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What 25 Years of Research Have Revealed About 9/11’s Long-Term Health Effects

Twenty-five years after 9/11, long-term monitoring of responders and survivors continues to reveal the complex health consequences of exposure to environmental toxins and hazardous materials.

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PD-L2 Blockade May Reduce Harmful Aging Cell Buildup

Blocking PD-L2 reduced senescent cell accumulation in aged mice and improved measures tied to metabolic function and physical strength.

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Cancer Treatment Genetic Effects in Healthy Cells May Reveal Clues to Side Effects and Resistance

Researchers used DNA sequencing to map mutations in normal tissue from cancer patients undergoing different types of treatment. They found significant differences in the genetic mutations in healthy tissue, depending on whether the patients received radiotherapy, chemotherapy, or chemoradiation.

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Samsung Biologics Signs $262 Million Manufacturing Agreement with European Pharma Firm

Alongside decisions involving capacity expansion, officials at Samsung Biologics announced that the company is pursuing opportunities to broaden its portfolio and address an increasingly diverse range of therapeutic modalities.

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Transcenta Therapeutics and WuXi Biologics Team Up to Accelerate Commercialization of HiCB Technology

Transcenta, headquartered in China and with a pipeline of over ten therapeutic antibody candidates, is a clinical-stage biopharmaceutical company with expertise in biologics discovery, translational research, clinical, and process development.

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CloudScope Enables Continuous Remote Monitoring of Brain Activity in Freely Moving Mice

Johns Hopkins researchers developed CloudScope, a cloud-based microscope enabling continuous, remote brain imaging in freely moving mice, revealing disease progression, seizures, cellular changes and behavior over extended periods.

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Bone Marrow-on-a-Chip Model Offers New Window Into Immune Cell Development and Behavior

By reproducing elements of human bone marrow on a chip, scientists have created a new tool that will help them gain new insights into how immune cells develop and function.

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Navigating the Regulatory Labyrinth: How Biotech Leaders Are Rethinking Strategy in an Uncertain Regulatory Era

The companies that emerge from this evolving regulatory cycle with clean, rigorous, globally positioned programs will find themselves in a structurally superior competitive position when the environment stabilizes.

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The Analytical Blueprint for Cell & Gene Therapy Success

This eBook brings together expert perspectives on several of the most pressing analytical topics facing today’s cell and gene therapy developers.

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Psilocybin Prevents Chemotherapy-Related Peripheral Neuropathy in Mice

A study found that psilocybin given before chemotherapy prevented the onset of nerve injury in mouse models, even after repeated treatment cycles, and also protected tumor-bearing mice from neuropathy, without impairing antitumor efficacy.

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Immune Cells Driving Alzheimer’s-Like Neurodegeneration Traced to Lymph Nodes

A study in mice traces immune cells that drive neurodegeneration to the body’s lymph nodes, suggesting that processes outside the brain contribute to the damage seen in various tauopathies.

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Watchmaker Genomics Boosts Manufacturing Capacity with Major Boulder Campus Expansion

The Flatiron Park facility in Colorado will serve as the Watchmaker Boulder Manufacturing Center of Excellence for reagent manufacturing and will house the company’s manufacturing, quality, R&D, and operations teams.

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